SCHEMBL9870874

SCHEMBL9870874

Clc1ccc([C]2CC2)cc1Cl

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 5/20 0.65
CYP1B1 Q16678 1/20 0.54
TP53 P04637 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
SLC6A3 Q01959 3/20 0.43
MAPT P10636 2/20 0.43
HTT P42858 2/20 0.43
HPGD P15428 2/20 0.43
ALDH1A1 P00352 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
NOTUM Q6P988 1/20 0.42
KDM4E B2RXH2 1/20 0.42
USP2 O75604 1/20 0.42
GAA P10253 1/20 0.42
PKM P14618 1/20 0.42
ALOX12 P18054 1/20 0.42
PTGS2 P35354 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6472818 0.90 AHR (0.59) AHRCYP1B1NPC1RAB9ASLC6A3
SCHEMBL4808905 0.88 AHR (0.56) AHRCYP1B1TP53NPC1RAB9A
SCHEMBL27997002 0.84 AHR (0.52) AHRCYP1B1SLC6A3MAPTHTT
SCHEMBL12473824 0.84 AHR (0.52) AHRCYP1B1NPC1RAB9ASLC6A3
SCHEMBL6075718 0.81 AHR (0.48) AHRCYP1B1SLC6A3SLC6A2
SCHEMBL21700370 0.81 AHR (0.48) AHRCYP1B1NPC1RAB9ASLC6A3
SCHEMBL21700368 0.81 AHR (0.48) AHRCYP1B1NPC1RAB9ASLC6A3
SCHEMBL29769221 0.80 AHR (1.00) AHRCYP1B1TP53NPC1RAB9A
SCHEMBL137915 0.80 AHR (1.00) AHRCYP1B1TP53NPC1RAB9A
SCHEMBL15517005 0.78 PTGS2 (0.43) AHRSLC6A3PTGS2PTGS1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5051447-A Applying aromatic oximes to plants, seeds or soils BASF AKTIENGESELLSCHAFT (DE) 1991-09-24 US disclosed
US-4952720-A Ortho-substituted benzyl carboxylates and fungicides which contain these compounds BASF AKTIENGSELLSCHAFT (DE) 1990-08-28 US disclosed