Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 2/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15516729 | 0.91 | PTGS2 (0.41) | PTGS2PTGS1KMOEGLN2AHR | |
| SCHEMBL19993855 | 0.90 | SLC6A3 (0.40) | PTGS2PTGS1KMOEGLN2AHR | |
| SCHEMBL29993075 | 0.83 | AHR (0.55) | PTGS2PTGS1KMOEGLN2AHR | |
| SCHEMBL15517645 | 0.82 | NISCH (0.49) | PTGS2PTGS1KMOAHRNISCH | |
| SCHEMBL21268669 | 0.78 | NOTUM (0.42) | PTGS2PTGS1KMOCYP11B1CYP11B2 | |
| SCHEMBL9870874 | 0.78 | AHR (0.65) | PTGS2PTGS1AHRSLC6A3SLC6A2 | |
| SCHEMBL12497411 | 0.77 | SIRT1 (0.40) | PTGS2PTGS1KMOSIRT1SLC6A3 | |
| SCHEMBL31067094 | 0.74 | AHR (0.46) | PTGS2PTGS1KMOEGLN2AHR | |
| SCHEMBL15516726 | 0.74 | PTGS2 (0.51) | PTGS2PTGS1KMOSLC6A3NISCH | |
| SCHEMBL3022768 | 0.73 | DAPK3 (0.45) | PTGS2PTGS1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2887802-A2 | METHODS OF SOIL PEST CONTROL | Syngenta Participations AG (CH) | 2015-07-01 | — | — | EP | disclosed |
| WO-2014029708-A1 | METHODS OF CONTROLLING INSECTS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-27 | — | — | WO | disclosed |
| WO-2014029706-A2 | METHODS OF CONTROLLING INSECTS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-27 | — | — | WO | disclosed |
| WO-2014029710-A2 | METHODS OF SOIL PEST CONTROL | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-27 | — | — | WO | disclosed |
| WO-2014029707-A1 | METHODS OF CONTROLLING INSECTS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-27 | — | — | WO | disclosed |
| WO-2014019609-A1 | METHODS OF PEST CONTROL IN SOYBEAN | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-06 | — | — | WO | disclosed |