Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 13/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023254 | 1.00 | HMGCR (0.84) | HMGCR | |
| SCHEMBL9527887 | 0.91 | HMGCR (1.00) | HMGCR | |
| SCHEMBL9872047 | 0.91 | HMGCR (1.00) | HMGCR | |
| SCHEMBL9872045 | 0.91 | HMGCR (1.00) | HMGCR | |
| SCHEMBL9022892 | 0.88 | HMGCR (1.00) | HMGCR | |
| Glenvastatin SCHEMBL1040745 | 0.88 | HMGCR (1.00) | HMGCR | |
| Glenvastatin SCHEMBL1660022 | 0.88 | HMGCR (1.00) | HMGCR | |
| Glenvastatin SCHEMBL1040744 | 0.88 | HMGCR (1.00) | HMGCR | |
| Glenvastatin SCHEMBL9872411 | 0.88 | HMGCR (1.00) | HMGCR | |
| Glenvastatin SCHEMBL49508 | 0.88 | HMGCR (1.00) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997837-A | Enzyme inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-05 | — | — | US | disclosed |
| US-4906624-A | 6-(((Substituted)pyridin-3-yl)alkyl)-and alkenyl)-tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis | WARNER-LAMBERT COMPANY (US) | 1990-03-06 | — | — | US | disclosed |