Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 6/20 | 0.61 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.61 |
| ▸ | PDK3 | Q15120 | 6/20 | 0.61 |
| ▸ | PDK4 | Q16654 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | AURKA | O14965 | 1/20 | 0.53 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10420550 | 0.89 | PDK1 (0.76) | PDK1PDK2PDK3PDK4MAPT | |
| SCHEMBL2072672 | 0.89 | MAPT (0.60) | PDK1PDK2PDK3PDK4MAPT | |
| SCHEMBL4610006 | 0.86 | PDK1 (0.81) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL6569621 | 0.86 | PDK1 (0.81) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL9870968 | 0.84 | PDK1 (0.52) | PDK1PDK2PDK3PDK4MAPT | |
| SCHEMBL9870149 | 0.83 | GAA (0.54) | PDK1PDK2PDK3PDK4MAPT | |
| SCHEMBL9869867 | 0.83 | ALDH1A1 (0.55) | PDK1PDK2PDK3PDK4MAPT | |
| SCHEMBL10420241 | 0.83 | MAPT (0.57) | PDK1PDK2PDK3PDK4MAPT | |
| SCHEMBL9869441 | 0.83 | PDK1 (0.51) | PDK1PDK2PDK3PDK4MAPT | |
| SCHEMBL9870871 | 0.81 | PDK1 (0.48) | PDK1PDK2PDK3PDK4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4962284-A | HERBICIDES, FUNGICIDES | ELI LILLY AND COMPANY (US) | 1990-10-09 | — | — | US | claimed |
| US-4826841-A | INSECTICIDES, MITICIDES | ELI LILLY AND COMPANY (US) | 1989-05-02 | — | — | US | claimed |
| US-4962284-A | HERBICIDES, FUNGICIDES | ELI LILLY AND COMPANY (US) | 1990-10-09 | — | — | US | disclosed |
| US-4826841-A | INSECTICIDES, MITICIDES | ELI LILLY AND COMPANY (US) | 1989-05-02 | — | — | US | disclosed |
| EP-0197756-A2 | Alkanoyl anilides | ELI LILLY AND COMPANY (US) | 1986-10-15 | — | — | EP | disclosed |
| EP-0197451-A2 | Energy submetering system | HONEYWELL INC. (US) | 1986-10-15 | — | — | EP | disclosed |