Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 1.00 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.79 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.79 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.79 |
| ▸ | MAOB | P27338 | 4/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.73 |
| ▸ | HPGD | P15428 | 4/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.73 |
| ▸ | MAPT | P10636 | 3/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.73 |
| ▸ | THRB | P10828 | 2/20 | 0.73 |
| ▸ | GLA | P06280 | 1/20 | 0.73 |
| ▸ | USP2 | O75604 | 1/20 | 0.71 |
| ▸ | RECQL | P46063 | 1/20 | 0.71 |
| ▸ | TP53 | P04637 | 3/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29435863 | 0.88 | CSNK2A2 (0.81) | ABCB1CSNK2A2CSNK2BCSNK2A1MAOB | |
| SCHEMBL26117897 | 0.88 | CSNK2A2 (0.81) | ABCB1CSNK2A2CSNK2BCSNK2A1MAOB | |
| 4,7-Dimethoxyflavone SCHEMBL3470601 | 0.87 | MAOB (1.00) | ABCB1CSNK2A2CSNK2BCSNK2A1MAOB | |
| SCHEMBL4400168 | 0.86 | FYN (0.81) | ABCB1CSNK2A2CSNK2BCSNK2A1MAOB | |
| SCHEMBL6555693 | 0.86 | PABPC1 (0.76) | ABCB1CSNK2A2CSNK2BCSNK2A1MAOB | |
| 3',4'-Dimethoxyflavone SCHEMBL1675954 | 0.84 | CYP3A4 (1.00) | ABCB1CSNK2A2CSNK2BCSNK2A1MAOB | |
| 3',4'-Dimethoxyflavone SCHEMBL29623082 | 0.84 | CYP3A4 (1.00) | ABCB1CSNK2A2CSNK2BCSNK2A1MAOB | |
| SCHEMBL4399922 | 0.84 | ABCB1 (0.72) | ABCB1CSNK2A2CSNK2BCSNK2A1MAOB | |
| SCHEMBL12830714 | 0.84 | ABCB1 (0.72) | ABCB1CSNK2A2CSNK2BCSNK2A1MAOB | |
| 3',4'-Dimethoxyflavone SCHEMBL28140373 | 0.83 | CYP3A4 (0.97) | ABCB1CSNK2A2CSNK2BCSNK2A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2494874-B1 | Control of flavor characteristics of fruit juice | TROPICANA PROD INC (US) | 2013-12-11 | — | — | EP | claimed |
| EP-2494874-A1 | Control of flavor characteristics of fruit juice | TROPICANA PRODUCTS, INC. (US) | 2012-09-05 | — | — | EP | claimed |
| EP-2186531-A2 | Improvement of the efficiency of pharmaceutical active agent-releasing medical products through combination with an inhibitor of the P-glycoprotein transport protein | BIOTRONIK VI Patent AG (CH) | 2010-05-19 | — | — | EP | claimed |
| US-20100119581-A1 | Medical Products That Release Pharmaceutically Active Substances | BIOTRONIK VI PATENT AG (CH) | 2010-05-13 | — | — | US | claimed |
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | claimed |
| EP-2730431-B1 | Rubber composition and tire with rubber containing flavone | GOODYEAR TIRE & RUBBER (US) | 2017-06-28 | — | — | EP | disclosed |
| US-8980352-B2 | Control of flavor characteristics of and indicator of freshness in fruit juice | TROPICANA PRODUCTS, INC. (US) | 2015-03-17 | — | — | US | disclosed |
| US-20140135433-A1 | TIRE WITH RUBBER CONTAINING FLAVONE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2014-05-15 | — | — | US | disclosed |
| EP-2730431-A1 | Rubber composition and tire with rubber containing flavone | The Goodyear Tire & Rubber Company (US) | 2014-05-14 | — | — | EP | disclosed |
| EP-2494874-B1 | Control of flavor characteristics of fruit juice | TROPICANA PROD INC (US) | 2013-12-11 | — | — | EP | disclosed |
| EP-2217098-B1 | CONTROL OF FLAVOR CHARACTERISTICS OF AND INDICATOR OF FRESHNESS IN FRUIT JUICE | TROPICANA PROD INC (US) | 2013-08-07 | — | — | EP | disclosed |
| US-20120239140-A1 | MEDICAL PRODUCT COMPRISING AN ACTIVE COATING | BIOTRONIK AG (CH) | 2012-09-20 | — | — | US | disclosed |
| US-20080287374-A1 | BREAST CANCER-RESISTANT PROTEIN INHIBITOR | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2008-11-20 | — | — | US | disclosed |
| EP-1391327-B1 | Tire with rubber containing flavone | GOODYEAR TIRE & RUBBER (US) | 2008-09-03 | — | — | EP | disclosed |
| US-20060135445-A1 | Breast cancer-resistant protein inhibitor | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2006-06-22 | — | — | US | disclosed |
| EP-1591112-A1 | BREAST CANCER-RESISTANT PROTEIN INHIBITOR | Kabushiki Kaisha Yakult Honsha (JP) | 2005-11-02 | — | — | EP | disclosed |
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | disclosed |
| EP-1391327-A1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2004-02-25 | — | — | EP | disclosed |
| WO-2003057210-A1 | COMPOSITIONS AND METHODS FOR INCREASING CELL PROLIFERATION COMPRISING A FLAVONOID | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2003-07-17 | — | — | WO | disclosed |
| US-20030125264-A1 | Methods For Treating Wounds | KIMBERLY-CLARK WORLDWIDE, INC. | 2003-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135445-A1 | Breast cancer-resistant protein inhibitor | ABCC1, BCR, BRCA1 | ABCB1 4/4885CSNK2A2 2298/4885CSNK2B 2245/4885 |
| US-20080287374-A1 | BREAST CANCER-RESISTANT PROTEIN INHIBITOR | ABCC1, BCR, BRCA1 | ABCB1 4/4885CSNK2A2 2298/4885CSNK2B 2245/4885 |
| US-20030125264-A1 | Methods For Treating Wounds | FGF2, MMP1, FIBP | ABCB1 2498/4885CSNK2A2 3078/4885CSNK2B 2902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.