Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.81 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.77 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.72 |
| ▸ | MEN1 | O00255 | 5/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.72 |
| ▸ | TNKS | O95271 | 3/20 | 0.72 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.72 |
| ▸ | TP53 | P04637 | 2/20 | 0.72 |
| ▸ | HPGD | P15428 | 5/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | GLA | P06280 | 1/20 | 0.70 |
| ▸ | THRB | P10828 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9663466 | 0.91 | CSNK2A2 (0.81) | FYNPABPC1CYP3A4MEN1KMT2A | |
| SCHEMBL29929667 | 0.91 | CSNK2A2 (0.81) | FYNPABPC1CYP3A4MEN1KMT2A | |
| SCHEMBL29435862 | 0.91 | CSNK2A2 (0.81) | FYNPABPC1CYP3A4MEN1KMT2A | |
| SCHEMBL30960382 | 0.91 | TNKS (0.71) | FYNPABPC1ABCB1CYP3A4MEN1 | |
| SCHEMBL1744293 | 0.91 | TNKS (0.71) | FYNPABPC1ABCB1CYP3A4MEN1 | |
| SCHEMBL18613228 | 0.90 | FYN (1.00) | FYNPABPC1ABCB1CYP3A4MEN1 | |
| SCHEMBL30521708 | 0.90 | FYN (1.00) | FYNPABPC1ABCB1CYP3A4MEN1 | |
| SCHEMBL5280241 | 0.88 | TERT (0.80) | FYNPABPC1ABCB1CYP3A4MEN1 | |
| SCHEMBL4399496 | 0.87 | PABPC1 (1.00) | FYNPABPC1ABCB1CYP3A4MEN1 | |
| 7,3',4'-Trimethoxyflavone SCHEMBL987112 | 0.86 | ABCB1 (1.00) | FYNABCB1CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807408-B1 | OXY SUBSTITUTED FLAVONES AS ANTIHYPERGLYCEMIC AND ANTIDYSLIPIDEMIC AGENTS | COUNCIL SCIENT IND RES (IN) | 2016-06-08 | — | — | EP | disclosed |
| US-7635779-B2 | Oxy substituted flavones as antihyperglycemic and antidyslipidemic agents | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-12-22 | — | — | US | disclosed |
| EP-1807408-A1 | OXY SUBSTITUTED FLAVONES AS ANTIHYPERGLYCEMIC AND ANTIDYSLIPIDEMIC AGENTS | Council of Scientific and Industrial Research (IN) | 2007-07-18 | — | — | EP | disclosed |
| US-20060178373-A1 | Oxy substituted flavones as antihyperglycemic and antidyslipidemic agents | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2006-08-10 | — | — | US | disclosed |
| WO-2006040621-A1 | OXY SUBSTITUTED FLAVONES AS ANTIHYPERGLYCEMIC AND ANTIDYSLIPIDEMIC AGENTS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-04-20 | — | — | WO | disclosed |
| US-7009062-B2 | Process for the preparation of flavone derivatives | MERCK PATENT GMBH (DE) | 2006-03-07 | — | — | US | disclosed |
| EP-1355898-B1 | METHOD FOR PRODUCING FLAVONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2005-10-12 | — | — | EP | disclosed |
| US-20040059100-A1 | Process for the preparation of flavone derivatives | EUROPEAN BRAND PARTICIPATIONS SA (LU) | 2004-03-25 | — | — | US | disclosed |
| EP-1355898-A1 | METHOD FOR PRODUCING FLAVONE DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-10-29 | — | — | EP | disclosed |
| WO-2002060889-A1 | METHOD FOR PRODUCING FLAVONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040059100-A1 | Process for the preparation of flavone derivatives | HK2, MAP2K5, MAP2K4 | FYN 2986/4885PABPC1 4683/4885ABCB1 2496/4885 |
| US-20060178373-A1 | Oxy substituted flavones as antihyperglycemic and antidyslipidemic agents | GPR119, LIPC, SLC5A2 | FYN 4143/4885PABPC1 4790/4885ABCB1 1033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.