Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 8/20 | 0.76 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | CCR3 | P51677 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | DRD4 | P21917 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872559 | 0.85 | DRD4 (0.78) | MCHR1SIGMAR1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1789399 | 0.82 | MCHR1 (0.76) | MCHR1SIGMAR1KMT2AMEN1DRD4 | |
| SCHEMBL2390512 | 0.82 | KMT2A (0.70) | MCHR1SIGMAR1KMT2AMEN1KDM4E | |
| SCHEMBL2958079 | 0.82 | SSTR5 (0.77) | MCHR1KMT2AMEN1SSTR5CCR3 | |
| SCHEMBL694949 | 0.82 | SIGMAR1 (0.82) | MCHR1SIGMAR1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2954268 | 0.82 | MCHR1 (0.58) | MCHR1SIGMAR1KMT2AMEN1SSTR5 | |
| SCHEMBL5577689 | 0.81 | CCR5 (0.61) | MCHR1SIGMAR1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2956222 | 0.80 | SSTR5 (0.67) | MCHR1SSTR5 | |
| SCHEMBL6500308 | 0.80 | SIGMAR1 (0.81) | MCHR1SIGMAR1 | |
| SCHEMBL9870172 | 0.80 | MEN1 (0.78) | MCHR1SIGMAR1KMT2AMEN1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028616-A | Antiarrhythmia Agents | G. D. SEARLE & CO. (US) | 1991-07-02 | — | — | US | disclosed |