Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.78 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.77 |
| ▸ | DRD4 | P21917 | 4/20 | 0.74 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.73 |
| ▸ | DRD2 | P14416 | 1/20 | 0.72 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.71 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | CCR2 | P41597 | 2/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870566 | 0.96 | MEN1 (0.73) | MEN1KMT2AMCHR1DRD4SIGMAR1 | |
| SCHEMBL694949 | 0.92 | SIGMAR1 (0.82) | MEN1KMT2AMCHR1DRD4SIGMAR1 | |
| SCHEMBL9852229 | 0.90 | SLC6A5 (0.75) | MEN1KMT2AMCHR1DRD4SIGMAR1 | |
| SCHEMBL61848 | 0.89 | TMEM97 (0.83) | MEN1KMT2AMCHR1DRD4SIGMAR1 | |
| SCHEMBL9872559 | 0.85 | DRD4 (0.78) | MEN1KMT2AMCHR1DRD4SIGMAR1 | |
| SCHEMBL31736417 | 0.85 | MCHR1 (0.77) | MEN1KMT2AMCHR1DRD4SIGMAR1 | |
| SCHEMBL3590338 | 0.85 | SIGMAR1 (0.73) | MEN1KMT2AMCHR1DRD4SIGMAR1 | |
| SCHEMBL7218186 | 0.84 | DRD4 (0.86) | MEN1KMT2AMCHR1DRD4SIGMAR1 | |
| SCHEMBL2233466 | 0.84 | KCNH2 (0.80) | MEN1KMT2AMCHR1DRD4SIGMAR1 | |
| SCHEMBL8706523 | 0.84 | DRD2 (1.00) | DRD4DRD2CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028616-A | Antiarrhythmia Agents | G. D. SEARLE & CO. (US) | 1991-07-02 | — | — | US | disclosed |