Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872175 | 0.90 | KDM4E (0.48) | KDM4EHTTALDH1A1MAPTHPGD | |
| SCHEMBL9571788 | 0.77 | ALDH1A1 (0.52) | KDM4EHTTALDH1A1HPGDKMT2A | |
| SCHEMBL9596229 | 0.76 | ALDH1A1 (0.50) | KDM4EHTTALDH1A1MAPTHPGD | |
| SCHEMBL9871416 | 0.72 | METAP1 (0.45) | KDM4EHTTALDH1A1MAPTHPGD | |
| SCHEMBL9871424 | 0.71 | MAPT (0.40) | KDM4EHTTALDH1A1MAPTHPGD | |
| SCHEMBL9870438 | 0.71 | CYP19A1 (0.48) | KDM4EHTTALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL9873069 | 0.71 | METAP1 (0.46) | KDM4EHTTALDH1A1MAPTHPGD | |
| SCHEMBL9870903 | 0.70 | ALDH1A1 (0.47) | KDM4EHTTALDH1A1HPGDKMT2A | |
| SCHEMBL11047658 | 0.69 | ALDH1A1 (0.81) | KDM4EHTTALDH1A1MAPTHPGD | |
| SCHEMBL829534 | 0.67 | MAPT (0.53) | KDM4EHTTALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030646-A | Treatment of diseases resulting from disfunction of seretoninergic system | ADIR ET COMPAGNIE (FR) | 1991-07-09 | — | — | US | disclosed |