Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9571788 | 0.91 | ALDH1A1 (0.52) | ALDH1A1TSHRGPR3HSD17B10PARP1 | |
| SCHEMBL1146660 | 0.75 | HTR2A (0.51) | ALDH1A1TSHRGPR3TP53CREBBP | |
| SCHEMBL30223533 | 0.75 | HTR2A (0.51) | ALDH1A1TSHRGPR3TP53CREBBP | |
| SCHEMBL7428637 | 0.75 | HTR2A (0.51) | ALDH1A1TSHRGPR3TP53CREBBP | |
| SCHEMBL984 | 0.71 | HTR2A (0.54) | ALDH1A1TSHRGPR3TP53CREBBP | |
| SCHEMBL9873015 | 0.71 | GPR3 (0.39) | ALDH1A1TSHRGPR3TP53HSD17B10 | |
| SCHEMBL9872175 | 0.70 | KDM4E (0.48) | ALDH1A1HSD17B10KDM4EHTTLMNA | |
| SCHEMBL9871263 | 0.70 | KDM4E (0.48) | ALDH1A1HSD17B10KDM4EHTTNTRK1 | |
| SCHEMBL9870845 | 0.69 | CYP3A4 (0.39) | ALDH1A1TSHRKMT2A | |
| SCHEMBL13324130 | 0.69 | TP53 (0.46) | ALDH1A1TSHRTP53CREBBPHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030646-A | Treatment of diseases resulting from disfunction of seretoninergic system | ADIR ET COMPAGNIE (FR) | 1991-07-09 | — | — | US | disclosed |