Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 5/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CCR6 | P51684 | 2/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757308 | 0.72 | HTR7 (0.48) | GAAMEN1KMT2AALDH1A1POLB | |
| SCHEMBL9290406 | 0.64 | MEN1 (0.61) | GAAMEN1KMT2AALDH1A1POLB | |
| SCHEMBL7484059 | 0.64 | MEN1 (0.61) | GAAMEN1KMT2AALDH1A1POLB | |
| SCHEMBL7912372 | 0.63 | TDP1 (0.67) | GAAMEN1KMT2AALDH1A1POLB | |
| SCHEMBL10526689 | 0.63 | TDP1 (0.74) | GAAMEN1KMT2AALDH1A1POLB | |
| Ammonia Solution, Strong SCHEMBL6416651 | 0.62 | MEN1 (0.68) | GAAMEN1KMT2AALDH1A1POLB | |
| SCHEMBL9150525 | 0.62 | ALDH1A1 (0.49) | GAAMEN1KMT2AALDH1A1POLB | |
| SCHEMBL29437334 | 0.62 | SMN1; SMN2 (0.63) | GAAMEN1KMT2AALDH1A1POLB | |
| SCHEMBL17992537 | 0.62 | SMN1; SMN2 (0.63) | GAAMEN1KMT2AALDH1A1POLB | |
| SCHEMBL29450701 | 0.61 | MEN1 (0.66) | GAAMEN1KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021420-A | Antiserotonine agents; central nervous system, gastroin-testinal and cardiovascular disorders | RHONE-POULENC SANTE (FR) | 1991-06-04 | — | — | US | disclosed |