Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870517 | 0.83 | HSP90AA1 (0.46) | ATMMAPTLMNAGAATDP1 | |
| SCHEMBL3257577 | 0.78 | SIGMAR1 (0.58) | ATMMAPTLMNAKDM4EGAA | |
| SCHEMBL9873115 | 0.77 | ATM (0.48) | ATMMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL13917942 | 0.74 | ATM (0.49) | ATMMAPTLMNAKDM4EGAA | |
| SCHEMBL9871534 | 0.70 | POLB (0.47) | ATMMAPTLMNAKDM4EGAA | |
| SCHEMBL5963879 | 0.70 | NPC1 (0.48) | MAPTLMNAKDM4EGAATDP1 | |
| SCHEMBL3362762 | 0.68 | NPC1 (0.52) | MAPTKDM4EGAATDP1SMN1; SMN2 | |
| SCHEMBL11540343 | 0.67 | MEN1 (0.45) | MAPTLMNAKDM4EGAATDP1 | |
| SCHEMBL29698721 | 0.67 | ADRA2A (0.39) | ATMLMNASMN1; SMN2SIGMAR1NPC1 | |
| SCHEMBL6360701 | 0.67 | NPC1 (0.45) | ATMMAPTLMNAKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019611-A | Tetrahydrotriazinethiones | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-05-28 | — | — | US | disclosed |
| EP-0278890-A2 | Non-staining and slightly-staining antiozonants | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1988-08-17 | — | — | EP | disclosed |