Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9643809 | 0.79 | MEN1 (0.46) | SMN1; SMN2NPC1RAB9AALDH1A1CYP1A2 | |
| SCHEMBL9871349 | 0.77 | ATM (0.51) | ATMMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9872761 | 0.77 | ATM (0.48) | ATMMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL28360007 | 0.69 | MAPT (0.45) | ATMMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL11069122 | 0.69 | NPC1 (0.58) | ATMMAPTSMN1; SMN2NPC1RAB9A | |
| Iodide SCHEMBL28356095 | 0.68 | MAPT (0.44) | ATMMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8976824 | 0.65 | NPC1 (0.54) | ATMMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9871942 | 0.64 | FAAH (0.34) | ATMMAPTSMN1; SMN2GRM2HTT | |
| SCHEMBL9870517 | 0.64 | HSP90AA1 (0.46) | ATMMAPTSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL16015518 | 0.63 | GRM2 (0.40) | ATMMAPTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019611-A | Tetrahydrotriazinethiones | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-05-28 | — | — | US | disclosed |