Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | PTPRF | P10586 | 1/20 | 0.53 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13958843 | 0.88 | MAPT (0.64) | MAPTMEN1KMT2ARAB9AIDO1 | |
| SCHEMBL19750850 | 0.85 | CHRM2 (0.62) | CHRM2PTPRFPTPN2PTPN1PTPN11 | |
| SCHEMBL9969587 | 0.82 | TSHR (0.53) | CHRM2MAPTMEN1LMNAKMT2A | |
| SCHEMBL7176354 | 0.82 | PTPRF (0.50) | CHRM2PTPRFPTPN2PTPN1PTPN11 | |
| SCHEMBL13958857 | 0.80 | KMT2A (0.57) | PTPN1MAPTMEN1LMNAKMT2A | |
| SCHEMBL5839383 | 0.79 | LTA4H (0.46) | MAPTLMNAHTTRAB9ALOXL2 | |
| SCHEMBL7039579 | 0.79 | ALDH1A1 (0.54) | CHRM2PTPRFPTPN2PTPN1PTPN11 | |
| SCHEMBL1938300 | 0.79 | CHRM2 (0.58) | CHRM2PTPRFPTPN2PTPN1PTPN11 | |
| SCHEMBL628651 | 0.78 | CHRM2 (0.72) | CHRM2PTPRFPTPN2PTPN1PTPN11 | |
| Hydrochloric Acid SCHEMBL2955466 | 0.77 | CHRM2 (0.56) | CHRM2PTPRFPTPN2PTPN1PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105566169-B | A kind of method that nitrone is prepared by secondary amine | 南阳师范学院 | 2017-08-01 | — | — | CN | claimed |
| US-9914740-B2 | Tricyclic pyrido-carboxamide derivatives as rock inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-03-13 | — | — | US | disclosed |
| US-9914740-B2 | Tricyclic pyrido-carboxamide derivatives as rock inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-03-13 | — | — | US | disclosed |
| CN-105566169-B | A kind of method that nitrone is prepared by secondary amine | 南阳师范学院 | 2017-08-01 | — | — | CN | disclosed |
| US-20160152628-A1 | TRICYCLIC PYRIDO-CARBOXAMIDE DERIVATIVES AS ROCK INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2016-06-02 | — | — | US | disclosed |
| US-5001233-A | Synthesis of hydroxylamines using dioxiranes | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 1991-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160152628-A1 | TRICYCLIC PYRIDO-CARBOXAMIDE DERIVATIVES AS ROCK INHIBITORS | MYLK, MYLK2, ROCK1 | CHRM2 1027/4885PTPRF 1013/4885PTPN2 378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.