Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876149 | 0.85 | MAPT (0.60) | MAPTHPGDPOLBGAARECQL | |
| SCHEMBL11611638 | 0.75 | MAPT (0.64) | MAPTHPGDPOLBGAARECQL | |
| SCHEMBL11455608 | 0.73 | BCL2A1 (0.60) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL8005849 | 0.72 | PKM (0.58) | MAPTHPGDPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL30198527 | 0.72 | PKM (0.58) | MAPTHPGDPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL12173010 | 0.71 | MEN1 (0.72) | MAPTHPGDALDH1A1SMN1; SMN2PKM | |
| SCHEMBL24939851 | 0.69 | MYC (0.62) | MAPTPOLBALDH1A1SMN1; SMN2PKM | |
| SCHEMBL9624054 | 0.68 | L3MBTL1 (0.55) | MAPTHPGDPOLBGAARECQL | |
| SCHEMBL3192339 | 0.66 | L3MBTL1 (0.70) | POLBALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL3196821 | 0.66 | L3MBTL1 (0.70) | POLBALDH1A1KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045108-A | Herbicidal and plant growth-regulating N-aryl-pyrrol-L-one and isoindol-2-one compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-03 | — | — | US | disclosed |
| EP-0403891-A1 | N-Aryl-nitrogen-heterocyclic compounds | BAYER AG (DE) | 1990-12-27 | — | — | EP | disclosed |