Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30065660 | 0.90 | CYP3A4 (0.46) | CYP3A4LMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL4531509 | 0.90 | CYP3A4 (0.46) | CYP3A4LMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL111247 | 0.82 | PRKCZ (0.46) | CYP3A4LMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL29375416 | 0.82 | PRKCZ (0.46) | CYP3A4LMNACYP1A2CYP2D6CYP2C9 | |
| Iodide SCHEMBL27879062 | 0.80 | PRKCZ (0.44) | CYP3A4LMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL17301339 | 0.75 | BACE1 (0.41) | CYP3A4LMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL27680594 | 0.74 | PRKCZ (0.40) | CYP3A4LMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL4068083 | 0.73 | AXL (0.55) | CYP3A4LMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL31732851 | 0.73 | CYP3A4 (0.50) | CYP3A4LMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL637008 | 0.73 | CYP3A4 (0.50) | CYP3A4LMNACYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021420-A | Antiserotonine agents; central nervous system, gastroin-testinal and cardiovascular disorders | RHONE-POULENC SANTE (FR) | 1991-06-04 | — | — | US | disclosed |