Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.37 |
| ▸ | CHRNG | P07510 | 1/20 | 0.37 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | CHRND | Q07001 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15257366 | 0.84 | KDM4E (0.41) | KDM4EAKR1B1CHRNA1CHRNGCHRNB1 | |
| SCHEMBL9443630 | 0.79 | KDM4E (0.39) | KDM4ECHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL17567325 | 0.75 | KDM4E (0.50) | KDM4EAKR1B1 | |
| SCHEMBL7693611 | 0.75 | KDM4E (0.41) | KDM4E | |
| SCHEMBL7048882 | 0.75 | KDM4E (0.41) | KDM4E | |
| SCHEMBL7048877 | 0.75 | KDM4E (0.41) | KDM4E | |
| SCHEMBL2139332 | 0.72 | KDM4E (0.50) | KDM4E | |
| SCHEMBL9765072 | 0.72 | ABCB1 (0.34) | KDM4E | |
| SCHEMBL9195110 | 0.72 | ABCC9 (0.40) | KDM4E | |
| SCHEMBL7048894 | 0.72 | ABCC9 (0.43) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006550-A | Skin disorder, arthritis, wound healing agents, dry eye syndrome | ALLERGAN, INC. (US) | 1991-04-09 | — | — | US | disclosed |