Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7048877 | 1.00 | KDM4E (0.41) | KDM4E | |
| SCHEMBL7693611 | 1.00 | KDM4E (0.41) | KDM4E | |
| SCHEMBL9876495 | 0.88 | ALDH1A1 (0.41) | KDM4E | |
| SCHEMBL10816510 | 0.85 | ABCC9 (0.33) | KDM4E | |
| SCHEMBL9742155 | 0.85 | KCNA5 (0.40) | — | |
| SCHEMBL10956358 | 0.85 | ALOX5 (0.45) | — | |
| SCHEMBL11394655 | 0.85 | ALOX5 (0.45) | — | |
| SCHEMBL482265 | 0.85 | ABCC9 (0.49) | — | |
| SCHEMBL482263 | 0.85 | ABCC9 (0.49) | — | |
| SCHEMBL11394662 | 0.85 | ALOX5 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091950-B1 | SUBSTITUTED BENZOPYRAN DERIVATIVES AND THEIR USE AS ANTICONVULSANTS | SMITHKLINE BEECHAM PLC (GB) | 2003-04-09 | — | — | EP | disclosed |
| US-6395909-B1 | DRUGS FOR ANTICONVULSANTS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-05-28 | — | — | US | disclosed |
| EP-1091950-A1 | SUBSTITUTED BENZOPYRAN DERIVATIVES AND THEIR USE AS ANTICONVULSANTS | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000000484-A1 | SUBSTITUTED BENZOPYRAN DERIVATIVES AND THEIR USE AS ANTICONVULSANTS | SMITHKLINE BEECHAM PLC (GB) | 2000-01-06 | — | — | WO | disclosed |
| EP-0389861-B1 | Benzopyran derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-08-23 | — | — | EP | disclosed |
| US-5391751-A | Hypotensive, antiarrhythmia, antiasthmatic agents | RED BALLOON INVESTMENT LIMITED (JE) | 1995-02-21 | — | — | US | disclosed |
| US-5104890-A | Potassium channel activtors; vasodilators | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1992-04-14 | — | — | US | disclosed |
| EP-0389861-A1 | Benzopyran derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-03 | — | — | EP | disclosed |
| EP-0120427-B1 | 3,4-Dihydro-thiaoxo-1-pyrrolidinyl-or piperidinyl-ZH-benzo[b]pyrons | BEECHAM GROUP PLC (GB) | 1988-12-21 | — | — | EP | disclosed |
| US-4647670-A | HYPOTENSIVE AGENTS | BEECHAM GROUP P.L.C. (GB) | 1987-03-03 | — | — | US | disclosed |
| US-4510152-A | Antihypertensive chromenes and chromans | BEECHAM GROUP P.L.C. (GB) | 1985-04-09 | — | — | US | disclosed |
| US-4496565-A | HYPOTENSIVE AGENTS | BEECHAM GROUP P.L.C. (GB) | 1985-01-29 | — | — | US | disclosed |
| US-4481214-A | 4-Acylaminobenzopyrans useful as anti-hypertensive agents | BEECHAM GROUP P.L.C. (GB) | 1984-11-06 | — | — | US | disclosed |
| EP-0120427-A1 | 3,4-Dihydro-thiaoxo-1-pyrrolidinyl-or piperidinyl-ZH-benzo[b]pyrons | BEECHAM GROUP PLC (GB) | 1984-10-03 | — | — | EP | disclosed |
| EP-0107423-A1 | Novel chromans and chromenes | BEECHAM GROUP PLC (GB) | 1984-05-02 | — | — | EP | disclosed |
| US-4446113-A | HYPOTENSIVE AGENTS | BEECHAM GROUP P.L.C. (GB) | 1984-05-01 | — | — | US | disclosed |
| EP-0095316-A1 | Pharmaceutically active aminobenzopyrans | BEECHAM GROUP PLC (GB) | 1983-11-30 | — | — | EP | disclosed |
| EP-0093535-A1 | Novel chromenes and chromans | BEECHAM GROUP PLC (GB) | 1983-11-09 | — | — | EP | disclosed |
| EP-0076075-A1 | Pharmaceutically active benzopyran compounds | BEECHAM GROUP PLC (GB) | 1983-04-06 | — | — | EP | disclosed |
| US-4251537-A | Hypotensive 3,4-dihydro-2,2-dimethyl-4-amino-2H-benzo[b]pyran-3-ols | BEECHAM GROUP LIMITED (GB) | 1981-02-17 | — | — | US | disclosed |