Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7693611 | 1.00 | KDM4E (0.41) | KDM4E | |
| SCHEMBL7048882 | 1.00 | KDM4E (0.41) | KDM4E | |
| SCHEMBL9876495 | 0.88 | ALDH1A1 (0.41) | KDM4E | |
| SCHEMBL10816510 | 0.85 | ABCC9 (0.33) | KDM4E | |
| SCHEMBL9742155 | 0.85 | KCNA5 (0.40) | — | |
| SCHEMBL10956358 | 0.85 | ALOX5 (0.45) | — | |
| SCHEMBL11394655 | 0.85 | ALOX5 (0.45) | — | |
| SCHEMBL482265 | 0.85 | ABCC9 (0.49) | — | |
| SCHEMBL482263 | 0.85 | ABCC9 (0.49) | — | |
| SCHEMBL11394662 | 0.85 | ALOX5 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091950-B1 | SUBSTITUTED BENZOPYRAN DERIVATIVES AND THEIR USE AS ANTICONVULSANTS | SMITHKLINE BEECHAM PLC (GB) | 2003-04-09 | — | — | EP | disclosed |
| US-6395909-B1 | DRUGS FOR ANTICONVULSANTS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-05-28 | — | — | US | disclosed |
| EP-1091950-A1 | SUBSTITUTED BENZOPYRAN DERIVATIVES AND THEIR USE AS ANTICONVULSANTS | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000000484-A1 | SUBSTITUTED BENZOPYRAN DERIVATIVES AND THEIR USE AS ANTICONVULSANTS | SMITHKLINE BEECHAM PLC (GB) | 2000-01-06 | — | — | WO | disclosed |