Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367787 | 0.78 | — | — | |
| SCHEMBL2021022 | 0.77 | — | — | |
| SCHEMBL19823058 | 0.76 | HTR1A (0.46) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL9200836 | 0.73 | LMNA (0.53) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL9367686 | 0.73 | — | — | |
| SCHEMBL9367638 | 0.73 | — | — | |
| SCHEMBL9367611 | 0.72 | — | — | |
| SCHEMBL30574757 | 0.71 | LMNA (0.53) | — | |
| SCHEMBL28161959 | 0.71 | HRH3 (0.60) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL9202092 | 0.70 | HRH3 (0.50) | HTR1AADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988699-A | Treatment of psychological disorders such as schizophrenia, as antipsychotic agents and hypotensive agents | WARNER-LAMBERT COMPANY (US) | 1991-01-29 | — | — | US | disclosed |