Dipyridyl

Dipyridyl

SCHEMBL9872270

c1ccc(-c2ccccn2)nc1.c1cnc2ncccc2c1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.67
LMNA P02545 3/20 0.67
CCR1 P32246 3/20 0.67
CCR5 P51681 3/20 0.67
CCR8 P51685 3/20 0.67
METAP1 P53582 3/20 0.67
CYP1A2 P05177 1/20 0.67
POLB P06746 1/20 0.67
BLM P54132 1/20 0.67
HIF1A Q16665 1/20 0.67
DOHH Q9BU89 1/20 0.67
P4HTM Q9NXG6 1/20 0.67
TP53 P04637 3/20 0.62
ALOX15 P16050 3/20 0.62
L3MBTL1 Q9Y468 3/20 0.62
HTT P42858 2/20 0.62
SMN1; SMN2 Q16637 2/20 0.62
TDP1 Q9NUW8 2/20 0.62
ALPL P05186 1/20 0.62
HSP90AA1 P07900 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10067161 0.87 KDM4E (0.59) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL28268549 0.85 KDM4E (0.82) KDM4ELMNACCR1CCR5CCR8
SCHEMBL8193 0.84 CCR1 (0.55) KDM4ELMNACCR1CCR5CCR8
SCHEMBL28304525 0.84 CCR1 (0.55) KDM4ELMNACCR1CCR5CCR8
SCHEMBL29354893 0.84 CCR1 (0.55) KDM4ELMNACCR1CCR5CCR8
Methyl Alcohol SCHEMBL28178318 0.82 LMNA (0.52) KDM4ELMNACCR1CCR5CCR8
Water SCHEMBL8327751 0.82 CCR1 (0.52) KDM4ELMNACCR1CCR5CCR8
Ammonia Solution, Strong SCHEMBL2732606 0.82 CCR1 (0.52) KDM4ELMNACCR1CCR5CCR8
Hydrochloric Acid SCHEMBL16337846 0.82 CCR1 (0.52) KDM4ELMNACCR1CCR5CCR8
Hydrochloric Acid SCHEMBL3704753 0.82 CCR1 (0.52) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5037932-A Coatings And Encapsulants DOW CORNING CORPORATION (US) 1991-08-06 US disclosed