Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.66 |
| ▸ | NPC1 | O15118 | 5/20 | 0.66 |
| ▸ | RAB9A | P51151 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5250483 | 0.88 | ALDH1A1 (0.70) | ALDH1A1NPC1RAB9AKMT2ANPSR1 | |
| SCHEMBL6673813 | 0.88 | NPSR1 (0.63) | ALDH1A1NPC1RAB9AKMT2ANPSR1 | |
| SCHEMBL17131834 | 0.86 | NPSR1 (0.61) | ALDH1A1NPC1RAB9AKMT2ANPSR1 | |
| SCHEMBL629972 | 0.86 | NPSR1 (0.61) | ALDH1A1NPC1RAB9AKMT2ANPSR1 | |
| SCHEMBL17202170 | 0.85 | ALDH1A1 (0.52) | ALDH1A1NPC1RAB9AKMT2ANPSR1 | |
| SCHEMBL28575888 | 0.82 | NPSR1 (0.57) | ALDH1A1NPC1RAB9AKMT2ANPSR1 | |
| SCHEMBL9808267 | 0.81 | NPC1 (0.43) | ALDH1A1NPC1RAB9AKMT2ANPSR1 | |
| SCHEMBL9760007 | 0.81 | ALDH1A1 (0.50) | ALDH1A1NPC1RAB9AKMT2ANPSR1 | |
| SCHEMBL629973 | 0.81 | NPSR1 (0.55) | ALDH1A1NPC1RAB9AKMT2ANPSR1 | |
| SCHEMBL4138868 | 0.81 | NPSR1 (0.55) | ALDH1A1NPC1RAB9AKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057524-A | Asthma, dermatitis | A. H. ROBINS COMPANY INCORPORATED (US) | 1991-10-15 | — | — | US | disclosed |