Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 6/20 | 0.40 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12844387 | 0.80 | MEN1 (0.46) | CYP2D6KMT2AMEN1HSD17B10KDM4E | |
| SCHEMBL24038267 | 0.80 | MEN1 (0.46) | CYP2D6KMT2AMEN1HSD17B10KDM4E | |
| SCHEMBL12141917 | 0.79 | MCOLN2 (0.47) | CYP2D6KMT2AMEN1HSD17B10KDM4E | |
| SCHEMBL9208351 | 0.76 | MCOLN2 (0.45) | CYP2D6KMT2AMEN1HSD17B10KDM4E | |
| SCHEMBL96014 | 0.75 | NPSR1 (0.40) | CYP2D6KMT2AMEN1HSD17B10KDM4E | |
| SCHEMBL96013 | 0.75 | FAAH (0.39) | CYP2D6KMT2AMEN1HSD17B10KDM4E | |
| SCHEMBL8881202 | 0.72 | DAGLA (0.39) | CYP2D6KMT2AMEN1HSD17B10KDM4E | |
| SCHEMBL8881199 | 0.72 | DAGLA (0.39) | CYP2D6KMT2AMEN1HSD17B10KDM4E | |
| SCHEMBL11642483 | 0.69 | MEN1 (0.46) | CYP2D6KMT2AMEN1HSD17B10KDM4E | |
| SCHEMBL6360844 | 0.68 | CYP1A2 (0.51) | KMT2AMEN1HSD17B10LMNAMCOLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073565-A | Atherosclerosis, anticholesterol | WARNER-LAMBERT COMPANY (US) | 1991-12-17 | — | — | US | disclosed |