Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL96014 | 0.88 | NPSR1 (0.40) | DAGLAMEN1KMT2ANPSR1MAOA | |
| SCHEMBL8881199 | 0.85 | DAGLA (0.39) | DAGLAMEN1KMT2ANPSR1MAOA | |
| SCHEMBL96013 | 0.81 | FAAH (0.39) | DAGLAMEN1KMT2ANPSR1MAOA | |
| SCHEMBL1779637 | 0.77 | ALDH1A1 (0.47) | DAGLAMEN1KMT2AALDH1A1CASP1 | |
| SCHEMBL24038267 | 0.74 | MEN1 (0.46) | MEN1KMT2ANPSR1MAOABRD4 | |
| SCHEMBL12844387 | 0.74 | MEN1 (0.46) | MEN1KMT2ANPSR1MAOABRD4 | |
| SCHEMBL9872410 | 0.72 | CYP2D6 (0.41) | MEN1KMT2ANPSR1MAOABRD4 | |
| SCHEMBL12141917 | 0.72 | MCOLN2 (0.47) | MEN1KMT2ANPSR1MAOABRD4 | |
| SCHEMBL9208351 | 0.70 | MCOLN2 (0.45) | MEN1KMT2ANPSR1MAOAALDH1A1 | |
| SCHEMBL7317875 | 0.70 | FAAH (0.36) | MEN1KMT2ANPSR1MAOAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703075-A | Antiatherosclerotic and antithrombotic 1-benzopyran-4-ones and 2-amino-1,3-benzoxazine-4-ones | PHARMACIA & UPJOHN COMPANY (US) | 1997-12-30 | — | — | US | disclosed |
| EP-0489877-B1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 2-AMINO-6-PHENYL-4H-PYRAN-4-ONES | UPJOHN CO (US) | 1995-09-20 | — | — | EP | disclosed |