Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 4/20 | 0.41 |
| ▸ | CDK2 | P24941 | 4/20 | 0.41 |
| ▸ | CCNK | O75909 | 3/20 | 0.41 |
| ▸ | CCND3 | P30281 | 3/20 | 0.41 |
| ▸ | CDK9 | P50750 | 3/20 | 0.41 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 9/20 | 0.37 |
| ▸ | GAA | P10253 | 8/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872551 | 0.85 | SMN1; SMN2 (0.36) | CCNA2CDK2CCNKCCND3CDK9 | |
| SCHEMBL9871945 | 0.83 | CCNA2 (0.37) | CCNA2CDK2CCNKCCND3CDK9 | |
| SCHEMBL9870517 | 0.82 | HSP90AA1 (0.46) | MAPTGAATDP1SMN1; SMN2HPGD | |
| SCHEMBL108882 | 0.74 | MAPT (0.54) | MAPTGAATDP1SMN1; SMN2TP53 | |
| SCHEMBL29653984 | 0.74 | MAPT (0.54) | MAPTGAATDP1SMN1; SMN2TP53 | |
| SCHEMBL9871349 | 0.72 | ATM (0.51) | MAPTGAATDP1SMN1; SMN2LMNA | |
| SCHEMBL7027050 | 0.69 | MAPT (0.64) | MAPTGAATDP1SMN1; SMN2TP53 | |
| SCHEMBL9871952 | 0.69 | LMNA (0.36) | MAPTGAASMN1; SMN2TP53HPGD | |
| SCHEMBL512863 | 0.69 | MAPT (0.48) | MAPTGAATDP1SMN1; SMN2TP53 | |
| SCHEMBL29940926 | 0.69 | HPGD (0.60) | MAPTGAATDP1TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019611-A | Tetrahydrotriazinethiones | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-05-28 | — | — | US | disclosed |
| EP-0278890-A2 | Non-staining and slightly-staining antiozonants | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1988-08-17 | — | — | EP | disclosed |