Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.35 |
| ▸ | DDX3X | O00571 | 2/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9871945 | 0.85 | CCNA2 (0.37) | LMNASMN1; SMN2MEN1POLBKMT2A | |
| SCHEMBL9872551 | 0.84 | SMN1; SMN2 (0.36) | LMNASMN1; SMN2MEN1POLBKMT2A | |
| SCHEMBL9429347 | 0.73 | DDX3X (0.56) | MEN1KMT2AMAPK10DDX3XMAPK13 | |
| SCHEMBL9871548 | 0.69 | ALDH1A1 (0.45) | LMNASMN1; SMN2MEN1POLBKMT2A | |
| SCHEMBL5082029 | 0.69 | DDX3X (0.62) | LMNASMN1; SMN2MEN1KMT2ADDX3X | |
| SCHEMBL9872546 | 0.69 | CCNA2 (0.41) | LMNASMN1; SMN2MEN1POLBKMT2A | |
| SCHEMBL3690304 | 0.68 | NPSR1 (0.64) | MAPK10DDX3XMAPK13MAPK12MAPK11 | |
| SCHEMBL3234606 | 0.66 | RAPGEF4 (0.61) | MEN1POLBKMT2ADDX3XMAPK13 | |
| SCHEMBL20609306 | 0.66 | RAPGEF4 (0.59) | LMNAMEN1KMT2ADDX3XMAPK13 | |
| SCHEMBL28695682 | 0.66 | FADS1 (0.62) | LMNASMN1; SMN2MEN1KMT2ADDX3X |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019611-A | Tetrahydrotriazinethiones | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-05-28 | — | — | US | disclosed |