Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1708834 | 0.76 | TSHR (0.44) | TNKS2HSD17B10KDM4EHPGDPOLB | |
| SCHEMBL9872560 | 0.69 | SLC6A2 (0.33) | HSD17B10KDM4EHPGDUSP2ESR1 | |
| SCHEMBL8977802 | 0.69 | ALDH1A1 (0.47) | HSD17B10KDM4EHPGDUSP2ESR1 | |
| SCHEMBL28556798 | 0.69 | TDP1 (0.42) | HSD17B10KDM4EHPGDUSP2ESR1 | |
| SCHEMBL11570849 | 0.67 | CYP19A1 (0.42) | HSD17B10KDM4EHPGDUSP2ESR1 | |
| SCHEMBL9635252 | 0.66 | TSHR (0.53) | TNKS2HSD17B10KDM4EHPGDPOLB | |
| SCHEMBL9635086 | 0.66 | BRD4 (0.45) | HSD17B10KDM4EHPGDPOLBALOX15 | |
| SCHEMBL13940537 | 0.66 | MEN1 (0.41) | HSD17B10KDM4EHPGDUSP2ESR1 | |
| SCHEMBL1443391 | 0.64 | TNKS2 (0.52) | TNKS2HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL12898666 | 0.64 | MAPT (0.52) | TNKS2HSD17B10KDM4EHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368063-B1 | PROCESS FOR THE CHLORINATION IN THE NUCLEUS OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1992-06-10 | — | — | EP | disclosed |
| US-4990707-A | Process for the ring chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |