Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 3/20 | 0.39 |
| ▸ | SENP2 | Q9HC62 | 5/20 | 0.38 |
| ▸ | SENP1 | Q9P0U3 | 4/20 | 0.38 |
| ▸ | SUMO2 | P61956 | 4/20 | 0.38 |
| ▸ | SUMO1 | P63165 | 4/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.38 |
| ▸ | SENP3 | Q9H4L4 | 3/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CD44 | P16070 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12136672 | 0.84 | CYP1A2 (0.50) | CYP1A2CYP2A6TTRSLC9A1SENP2 | |
| SCHEMBL10900215 | 0.84 | TTR (0.61) | TTRAURKAAURKBSENP2SENP1 | |
| SCHEMBL10786218 | 0.82 | CYP1A2 (0.48) | CYP1A2CYP2A6TTRAURKAAURKB | |
| SCHEMBL7753514 | 0.81 | AURKA (0.54) | CYP1A2TTRAURKAAURKBSENP2 | |
| SCHEMBL313372 | 0.81 | TTR (0.68) | CYP1A2TTRAURKAAURKBSENP2 | |
| SCHEMBL30322685 | 0.81 | TTR (0.68) | CYP1A2TTRAURKAAURKBSENP2 | |
| SCHEMBL7753519 | 0.80 | TTR (0.41) | TTRAURKAAURKBSENP2SENP1 | |
| SCHEMBL615250 | 0.80 | CD44 (0.46) | TTRAURKAAURKBSENP2SENP1 | |
| SCHEMBL9274363 | 0.79 | TTR (0.66) | CYP1A2TTRAURKAAURKBSENP2 | |
| SCHEMBL20514928 | 0.79 | TTR (0.66) | CYP1A2TTRAURKAAURKBSENP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037449-A | For dyeing or printing cotton or wool | CIBA-GEIGY CORPORATION (US) | 1991-08-06 | — | — | US | disclosed |
| EP-0356394-A2 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1990-02-28 | — | — | EP | disclosed |