Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 3/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.34 |
| ▸ | SENP3 | Q9H4L4 | 2/20 | 0.33 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.33 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745105 | 0.85 | CASP6 (0.53) | MEN1KMT2ACASP6MAPTMAPK1 | |
| SCHEMBL27409133 | 0.83 | TTR (0.51) | TTRAURKAAURKBIDO1KEAP1 | |
| SCHEMBL10900215 | 0.81 | TTR (0.61) | TTRAURKAAURKBIDO1KEAP1 | |
| SCHEMBL8752095 | 0.80 | CASP6 (0.42) | HTR6MEN1KMT2ACASP6SENP3 | |
| SCHEMBL9872607 | 0.80 | CYP1A2 (0.45) | TTRAURKAAURKBSENP3SENP2 | |
| SCHEMBL4650350 | 0.79 | TTR (0.37) | TTRAURKAAURKBSENP3SENP2 | |
| SCHEMBL313372 | 0.78 | TTR (0.68) | TTRAURKAAURKBMEN1KMT2A | |
| SCHEMBL30322685 | 0.78 | TTR (0.68) | TTRAURKAAURKBMEN1KMT2A | |
| SCHEMBL7753514 | 0.78 | AURKA (0.54) | TTRAURKAAURKBIDO1MEN1 | |
| SCHEMBL20514928 | 0.77 | TTR (0.66) | TTRAURKAAURKBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097970-A2 | Water-soluble monoazo compounds, process for their preparation and their use as dyestuffs | DyStar Textilfarben GmbH & Co. Deutschland KG (DE) | 2001-05-09 | — | — | EP | disclosed |
| EP-1075500-A1 | WATER-SOLUBLE MONOAZO COMPOUNDS, METHOD FOR PRODUCING SAME AND THEIR USE AS DYES | DyStar Textilfarben GmbH & Co. Deutschland KG (DE) | 2001-02-14 | — | — | EP | disclosed |
| WO-1999058612-A1 | WATER-SOLUBLE MONOAZO COMPOUNDS, METHOD FOR PRODUCING SAME AND THEIR USE AS DYES | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 1999-11-18 | — | — | WO | disclosed |
| EP-0538785-B1 | Water-soluble fiber-reactive dyes, process for their preparation and their use | HOECHST AG (DE) | 1997-04-09 | — | — | EP | disclosed |
| EP-0511246-B1 | WATER-SOLUBLE DYES WHICH REACT WITH FIBRES, PROCESS FOR PRODUCING THEM AND THEIR USE | HOECHST AG (DE) | 1994-09-07 | — | — | EP | disclosed |
| EP-0388864-B1 | Water-soluble, fibre-reactive dyes, method of their preparation and use | HOECHST AG (DE) | 1994-02-02 | — | — | EP | disclosed |
| US-5278292-A | Aromatic sulfonyl water-soluble color materials | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-01-11 | — | — | US | disclosed |
| EP-0471702-B1 | WATER-SOLUBLE REACTIVE DYES FOR FIBRES, THEIR PREPARATION AND USE | HOECHST AG (DE) | 1993-12-29 | — | — | EP | disclosed |
| US-5231172-A | Water solubility | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-27 | — | — | US | disclosed |
| US-5227475-A | WATER-SOLUBLE FIBER-REACTIVE DYESTUFFS CONTAINING A CYANAMIDO-SUBSTITUTED TRIAZINYLAMINO-GROUPING, AND A PROCESS FOR DYEING WITH THE USE OF THESE DYES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-13 | — | — | US | disclosed |
| EP-0538785-A2 | Water-soluble fiber-reactive dyes, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-04-28 | — | — | EP | disclosed |
| EP-0511246-A1 | WATER-SOLUBLE DYES WHICH REACT WITH FIBRES, PROCESS FOR PRODUCING THEM AND THEIR USE. | HOECHST AG (DE) | 1992-11-04 | — | — | EP | disclosed |
| WO-1991010709-A1 | WATER-SOLUBLE DYES WHICH REACT WITH FIBRES, PROCESS FOR PRODUCING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-07-25 | — | — | WO | disclosed |
| US-5021558-A | Color strength, fastness | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-06-04 | — | — | US | disclosed |
| EP-0388864-A2 | Water-soluble, fibre-reactive dyes, method of their preparation and use | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-09-26 | — | — | EP | disclosed |
| EP-0385426-A1 | Water soluble reactive dyes, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-09-05 | — | — | EP | disclosed |