Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.59 |
| ▸ | HPGD | P15428 | 8/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872054 | 0.86 | HPGD (0.56) | KDM4EALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL9872630 | 0.84 | CTSV (0.57) | KDM4EALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL9872034 | 0.83 | KMT2A (0.56) | KDM4EALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL9872701 | 0.79 | HPGD (0.43) | KDM4EALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL9872570 | 0.79 | CYP19A1 (0.46) | KDM4EALDH1A1HPGDLMNANPC1 | |
| SCHEMBL9874829 | 0.78 | HPGD (0.60) | KDM4EALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL6534639 | 0.74 | HPGD (1.00) | KDM4EALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL29411859 | 0.74 | HPGD (1.00) | KDM4EALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL19032114 | 0.74 | MAPT (0.49) | KDM4EALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL9874866 | 0.73 | NPC1 (0.47) | KDM4EALDH1A1HPGDSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017576-A | Antianxiolytic, hypnotic, anticonvulsant, antiepileptic | RHONE-POULENC SANTE (FR) | 1991-05-21 | — | — | US | disclosed |