Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | BPTF | Q12830 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | PRKACG | P22612 | 1/20 | 0.39 |
| ▸ | PRKACB | P22694 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872497 | 0.68 | BPTF (0.42) | ALDH1A1HPGDMAPTKDM4ELMNA | |
| SCHEMBL11604601 | 0.67 | MEN1 (0.55) | ALDH1A1HPGDMAPTKDM4ETP53 | |
| SCHEMBL11564869 | 0.66 | ALDH1A1 (0.45) | ALDH1A1HPGDMAPTKDM4ELMNA | |
| SCHEMBL24785207 | 0.63 | BPTF (0.51) | ALDH1A1HPGDMAPTKDM4ETP53 | |
| SCHEMBL11557686 | 0.63 | ALDH1A1 (0.43) | ALDH1A1HPGDMAPTKDM4ELMNA | |
| SCHEMBL24785211 | 0.63 | ALDH1A1 (0.50) | ALDH1A1HPGDMAPTKDM4ETP53 | |
| SCHEMBL11064868 | 0.62 | BPTF (0.48) | ALDH1A1HPGDMAPTKDM4ENPSR1 | |
| SCHEMBL24785880 | 0.62 | ALDH1A1 (0.47) | ALDH1A1HPGDMAPTKDM4EGAA | |
| SCHEMBL23334745 | 0.62 | BPTF (0.46) | ALDH1A1HPGDMAPTKDM4ELMNA | |
| SCHEMBL26265515 | 0.61 | ALDH1A1 (0.52) | ALDH1A1HPGDMAPTKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2264772-A | — | — | None | — | — | JP | disclosed |
| US-5064962-A | DIAMINOTHIOPHENES | BASF AKTIENGESELLSCHAFT (DE) | 1991-11-12 | — | — | US | disclosed |
| JP-H02264772-A | DIAMINOTHIOPHENE AND ITS PREPARATION | BASF AG | 1990-10-29 | — | — | JP | disclosed |
| EP-0384314-A2 | Diaminothiophenes | BASF Aktiengesellschaft (DE) | 1990-08-29 | — | — | EP | disclosed |