Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 6/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | PRKACG | P22612 | 1/20 | 0.36 |
| ▸ | PRKACB | P22694 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11557686 | 0.98 | ALDH1A1 (0.43) | ALDH1A1TP53HPGDKDM4ELMNA | |
| SCHEMBL724741 | 0.83 | CTSK (0.45) | ALDH1A1TP53HPGDKDM4EMAPT | |
| SCHEMBL8555731 | 0.66 | — | — | |
| SCHEMBL9872797 | 0.66 | ALDH1A1 (0.42) | ALDH1A1TP53HPGDKDM4ELMNA | |
| SCHEMBL11557534 | 0.66 | ALDH1A1 (0.41) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL11564103 | 0.65 | — | — | |
| SCHEMBL3140235 | 0.63 | ALOX15 (0.47) | ALDH1A1TP53HPGDKDM4EMAPT | |
| SCHEMBL16432510 | 0.63 | HTR1A (0.45) | ALDH1A1HPGDKDM4E | |
| SCHEMBL9162883 | 0.63 | SMN1; SMN2 (0.53) | ALDH1A1TP53HPGDKDM4ELMNA | |
| SCHEMBL6845036 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4153607-A | Process for the production of 4,5-disubstituted thiazoles | BASF AKTIENGESELLSCHAFT (DE) | 1979-05-08 | — | — | US | disclosed |