Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | RORB | Q92753 | 2/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875803 | 0.82 | HTR2C (0.41) | HTR2CHTR7 | |
| SCHEMBL8024707 | 0.78 | HTR2C (0.41) | HTR2CGRIN1GRIN2BHTR7S1PR5 | |
| SCHEMBL9530357 | 0.75 | HTR2C (0.47) | HTR2CGRIN1GRIN2BCNR2 | |
| SCHEMBL8074288 | 0.74 | HTR2C (0.44) | HTR2CGRIN1GRIN2BS1PR5 | |
| SCHEMBL7439313 | 0.74 | MAOB (0.46) | HTR2CHTR7S1PR5 | |
| SCHEMBL7435086 | 0.73 | HTR2C (0.49) | HTR2CGRIN1GRIN2BCNR2S1PR5 | |
| SCHEMBL8540798 | 0.73 | HTR2C (0.44) | HTR2CPTPN5GRIN1GRIN2BCNR2 | |
| SCHEMBL8507430 | 0.72 | HTR2C (0.41) | HTR2CS1PR5 | |
| SCHEMBL7100010 | 0.71 | HTR2C (0.43) | HTR2CHTR7S1PR5 | |
| SCHEMBL10972228 | 0.71 | HTR2C (0.41) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991008200-A1 | NOVEL TETRAHYDROPYRIDINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS AS ACTIVE AGENTS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1991-06-13 | — | — | WO | claimed |