Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.51 |
| ▸ | HTR2C | P28335 | 5/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9874525 | 0.99 | HTR2A (0.50) | HTR2AHTR2CDRD2CYP2C19CYP2D6 | |
| Hydrochloric Acid SCHEMBL9874057 | 0.94 | HTR2A (0.49) | HTR2AHTR2CDRD2CYP2C19CYP2D6 | |
| Hydrochloric Acid SCHEMBL9874345 | 0.82 | HTR2A (0.46) | HTR2AHTR2CDRD2CYP2D6HTR7 | |
| Hydrochloric Acid SCHEMBL9874132 | 0.82 | HTR2A (0.57) | HTR2AHTR2CDRD2CYP2C19CYP2D6 | |
| Hydrochloric Acid SCHEMBL9872277 | 0.80 | HSD11B1 (0.49) | HTR2AHTR2CDRD2CYP2C19CYP2D6 | |
| Hydrochloric Acid SCHEMBL9875514 | 0.77 | SSTR5 (0.51) | DRD2KMT2AHPGDALDH1A1DRD4 | |
| SCHEMBL10642471 | 0.75 | HSD11B1 (0.50) | HTR2AHTR2CDRD2CYP2C19CYP2D6 | |
| Hydrochloric Acid SCHEMBL9872598 | 0.75 | THRB (0.54) | KMT2AMEN1ALDH1A1SLC6A4KDM4E | |
| Hydrochloric Acid SCHEMBL9366460 | 0.74 | HSD11B1 (0.49) | HTR2AHTR2CDRD2CYP2C19CYP2D6 | |
| SCHEMBL14318600 | 0.74 | HTR2A (0.81) | HTR2AHTR2CCYP2D6HTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983606-A | Pharmaceutically-active phthalazine compounds | ZAMBON GROUP S.P.A. (IT) | 1991-01-08 | — | — | US | disclosed |