Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTR1F | P30939 | 1/20 | 0.45 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9366460 | 0.99 | HSD11B1 (0.49) | HSD11B1LMNAKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12115050 | 0.81 | KDM4E (0.46) | HSD11B1HTR2AHTR2CGAAKDM4E | |
| SCHEMBL9872917 | 0.75 | HTR2A (0.51) | HSD11B1LMNAKMT2ASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9874525 | 0.74 | HTR2A (0.50) | LMNAKMT2AALDH1A1DRD2HTR2A | |
| SCHEMBL10704614 | 0.74 | HSD11B1 (0.55) | HSD11B1LMNAKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10706427 | 0.73 | HSD11B1 (0.55) | HSD11B1LMNAKMT2ASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9874057 | 0.73 | HTR2A (0.49) | DRD2HTR2AHTR2CCYP2C19CYP2D6 | |
| SCHEMBL10705820 | 0.72 | ALDH1A1 (0.55) | HSD11B1LMNAKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3058287 | 0.72 | PDE10A (0.55) | HSD11B1LMNAKMT2AALDH1A1MAPT | |
| SCHEMBL8375893 | 0.71 | STAT3 (0.56) | HSD11B1LMNAKMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288563-A1 | CYCLIC AMINE DERIVATIVES | Eisai Co., Ltd. (JP) | 1988-11-02 | — | — | EP | claimed |