SCHEMBL9873074

SCHEMBL9873074

CC(C)(C)c1cc(CSC(N)=S)cc(C(C)(C)C)c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.47
TSHR P16473 4/20 0.47
LMNA P02545 3/20 0.47
GAA P10253 3/20 0.47
MAPK1 P28482 3/20 0.46
MEN1 O00255 3/20 0.46
CYP1A2 P05177 3/20 0.46
CYP3A4 P08684 3/20 0.46
BLM P54132 3/20 0.46
KMT2A Q03164 3/20 0.46
HIF1A Q16665 3/20 0.46
ALOX15 P16050 3/20 0.46
ATM Q13315 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
GMNN O75496 2/20 0.46
CYP2C9 P11712 2/20 0.46
NFKB1 P19838 2/20 0.46
CYP2C19 P33261 2/20 0.46
PMP22 Q01453 2/20 0.46
GABBR2 O75899 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10880084 0.80 ALDH1A1 (0.53) ALDH1A1TSHRLMNAGAAMAPK1
SCHEMBL11289791 0.78 LMNA (0.49) ALDH1A1TSHRLMNAGAAMAPK1
SCHEMBL38964 0.77 ALDH1A1 (0.57) ALDH1A1TSHRLMNAGAAMAPK1
SCHEMBL295548 0.77 ALDH1A1 (0.57) ALDH1A1TSHRLMNAGAAMAPK1
SCHEMBL698586 0.77 ALDH1A1 (0.49) ALDH1A1TSHRLMNAGAAMAPK1
SCHEMBL9647793 0.77 ALDH1A1 (0.52) ALDH1A1TSHRLMNAGAAMAPK1
SCHEMBL9478510 0.76 ALDH1A1 (0.55) ALDH1A1TSHRLMNAGAAMAPK1
Hydrogen Sulfide SCHEMBL28290635 0.76 ALDH1A1 (0.55) ALDH1A1TSHRLMNAGAAMAPK1
SCHEMBL11612147 0.75 ALDH1A1 (0.44) ALDH1A1TSHRLMNAGAAMAPK1
SCHEMBL9507166 0.74 ALDH1A1 (0.53) ALDH1A1TSHRLMNAGAAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5070007-A OF COUPLERS AND DYES FORMED FROM THEM CIBA-GEIGY AG (CH) 1991-12-03 US disclosed
US-5006665-A Light, heat, oxidation stabilizers for color photography CIBA-GEIGY AG (CH) 1991-04-09 US disclosed