Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.34 |
| ▸ | TUBB | P07437 | 2/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.34 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.34 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27336186 | 0.90 | GPR84 (0.36) | GPR84NPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL27446408 | 0.85 | ALDH1A1 (0.34) | GPR84ALDH1A1MAPK1PARP1TLR7 | |
| SCHEMBL27322051 | 0.84 | PARP1 (0.40) | GPR84ALDH1A1MAPK1PARP1LMNA | |
| SCHEMBL27318209 | 0.83 | GPR84 (0.38) | GPR84ALDH1A1MAPK1PARP1GSK3B | |
| SCHEMBL7303318 | 0.83 | NPSR1 (0.41) | GPR84NPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL27334926 | 0.83 | GPR84 (0.41) | GPR84NPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL8812731 | 0.82 | GPR84 (0.42) | GPR84MAPT | |
| SCHEMBL833 | 0.82 | GPR84 (0.37) | GPR84NPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL27542325 | 0.82 | GPR84 (0.37) | GPR84NPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL7398766 | 0.81 | HPGD (0.37) | NPC1RAB9AALDH1A1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1121859-C | Process for preparing pharmaceutical composition for treatment or prevention hypertension | SNAKYO CO LTD (JP) | 2003-09-24 | — | — | CN | disclosed |
| CN-1101384-C | Process for preparing 1-biphenylmethylimidazole derivatives | SANKYO CO (JP) | 2003-02-12 | — | — | CN | disclosed |
| CN-1045770-C | Process for preparing 1-biphenylmethylimidazole derivatives | SANKYO CO (JP) | 1999-10-20 | — | — | CN | disclosed |
| CN-1189490-A | Process for preparing 1-biphenylmethylimidazole derivatives | SANKYO CO (JP) | 1998-08-05 | — | — | CN | disclosed |
| CN-1188645-A | Process for preparing pharmaceutical composition for treatment or prevention hypertension | SNAKYO CO LTD (JP) | 1998-07-29 | — | — | CN | disclosed |
| CN-1065063-A | 1-Biphenylmethylimidazole derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1992-10-07 | — | — | CN | disclosed |
| WO-1991019715-A1 | 1H-SUBSTITUTED-IMIDAZO[4,5-d]PYRIDAZINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1991-12-26 | — | — | WO | disclosed |