Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27585785 | 0.82 | KDM4E (0.41) | MTORRAB9ATSHRKDM4EHSD17B10 | |
| SCHEMBL2001481 | 0.81 | TSHR (0.52) | MTORRAB9ATSHRKDM4EHSD17B10 | |
| SCHEMBL9871258 | 0.80 | MTOR (0.38) | MTORRAB9ATSHRCA12CA1 | |
| SCHEMBL9874781 | 0.80 | MTOR (0.38) | MTORRAB9ATSHRCA12CA1 | |
| SCHEMBL3694807 | 0.77 | TSHR (0.53) | TSHRKDM4EHSD17B10CA12CA1 | |
| SCHEMBL27213906 | 0.76 | CA12 (0.47) | TSHRKDM4EHSD17B10CA12CA1 | |
| SCHEMBL9442736 | 0.75 | HPGD (0.52) | KDM4EHSD17B10MAPTALDH1A1LMNA | |
| SCHEMBL9873432 | 0.75 | POLB (0.35) | MTORRAB9ATSHRKDM4EHSD17B10 | |
| SCHEMBL9873451 | 0.75 | MTOR (0.37) | MTORRAB9ATSHRKDM4EHSD17B10 | |
| SCHEMBL2184188 | 0.74 | TSHR (0.48) | TSHRKDM4EHSD17B10CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990508-A | Reduced side effects | TOYAMA CHEMICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |