Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873432 | 0.77 | POLB (0.35) | MTORRAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL9873755 | 0.75 | MTOR (0.42) | MTORRAB9AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9875122 | 0.71 | NFKB1 (0.33) | MTORRAB9APOLBTSHRKMT2A | |
| SCHEMBL2001481 | 0.71 | TSHR (0.52) | MTORRAB9AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9871258 | 0.70 | MTOR (0.38) | MTORRAB9AALDH1A1MAPTHTT | |
| SCHEMBL9874781 | 0.70 | MTOR (0.38) | MTORRAB9AALDH1A1MAPTHTT | |
| SCHEMBL27213906 | 0.67 | CA12 (0.47) | ALDH1A1KDM4EHSD17B10MAPTHTT | |
| SCHEMBL9873963 | 0.67 | TSHR (0.36) | MTORRAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL9874142 | 0.66 | TSHR (0.42) | ALDH1A1KDM4EHPGDMAPTHTT | |
| SCHEMBL27547583 | 0.66 | TSHR (0.42) | ALDH1A1KDM4EHSD17B10MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990508-A | Reduced side effects | TOYAMA CHEMICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |