Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10775425 | 0.89 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1ACELMNANPSR1 | |
| SCHEMBL18297050 | 0.85 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1ACELMNANPSR1 | |
| SCHEMBL10776986 | 0.85 | PREP (0.55) | ALDH1A1ACELMNA | |
| SCHEMBL9872312 | 0.83 | SLC6A1 (0.54) | ALDH1A1L3MBTL1SLC6A1 | |
| SCHEMBL9872319 | 0.83 | SLC6A1 (0.54) | ALDH1A1L3MBTL1SLC6A1 | |
| SCHEMBL9873547 | 0.82 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1SLC6A1 | |
| SCHEMBL9873550 | 0.82 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1SLC6A1 | |
| SCHEMBL10771620 | 0.80 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL15723639 | 0.78 | PIK3CD (0.58) | ALDH1A1L3MBTL1NPSR1CYP3A4CYP2D6 | |
| SCHEMBL21715104 | 0.78 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051444-A | Pyrrolidine derivatives as anti-amnesia agents | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-09-24 | — | — | US | disclosed |