Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873809 | 0.86 | LMNA (0.36) | LMNATSHRTP53ALDH1A1MAPT | |
| SCHEMBL9874790 | 0.81 | TSHR (0.38) | LMNATSHRTP53ALDH1A1MAPT | |
| SCHEMBL9873509 | 0.78 | TSHR (0.43) | LMNATSHRTP53ALDH1A1MAPT | |
| SCHEMBL9873486 | 0.77 | TSHR (0.41) | LMNATSHRTP53ALDH1A1MAPT | |
| SCHEMBL9875016 | 0.76 | TDP1 (0.42) | LMNATSHRTP53ALDH1A1MAPT | |
| SCHEMBL9873569 | 0.75 | TP53 (0.41) | LMNATSHRTP53ALDH1A1MAPT | |
| SCHEMBL9873566 | 0.75 | TP53 (0.41) | LMNATSHRTP53ALDH1A1MAPT | |
| SCHEMBL8628876 | 0.74 | GSK3B (0.48) | LMNAOPRM1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL8601039 | 0.73 | KDM4E (0.36) | LMNAOPRM1OPRD1OPRK1KCNA3 | |
| SCHEMBL28804542 | 0.72 | TSHR (0.36) | LMNATSHRTP53ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990508-A | Reduced side effects | TOYAMA CHEMICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |