Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28804542 | 0.82 | TSHR (0.36) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL9874015 | 0.81 | LMNA (0.40) | TSHRKDM4EMAPTALOX15ALDH1A1 | |
| SCHEMBL9873963 | 0.81 | TSHR (0.36) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL2001481 | 0.77 | TSHR (0.52) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL27213906 | 0.73 | CA12 (0.47) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL9874569 | 0.73 | RORC (0.41) | TSHRKDM4EALDH1A1SMN1; SMN2GAA | |
| SCHEMBL9874142 | 0.71 | TSHR (0.42) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL2184188 | 0.71 | TSHR (0.48) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL9873755 | 0.70 | MTOR (0.42) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL7813719 | 0.70 | TSHR (0.52) | TSHRCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990508-A | Reduced side effects | TOYAMA CHEMICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |