Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874763 | 0.80 | TSHR (0.55) | KMT2AKEAP1NFE2L2ALDH1A1 | |
| Phenol SCHEMBL11598564 | 0.79 | SNCA (0.58) | SNCANPC1RAB9ANSD2DUSP3 | |
| Sulfosalicylic SCHEMBL9874624 | 0.79 | ALDH1A1 (0.65) | BCL2L1MCL1MEN1KMT2AALDH1A1 | |
| SCHEMBL9875339 | 0.77 | KEAP1 (0.52) | MEN1KMT2AKEAP1NFE2L2ALDH1A1 | |
| Sulfuric Acid SCHEMBL9324944 | 0.77 | HSP90AA1 (0.43) | NPC1RAB9AKMT2AKEAP1NFE2L2 | |
| SCHEMBL565054 | 0.77 | LMNA (0.60) | SNCANPC1RAB9ANSD2DUSP3 | |
| SCHEMBL1893729 | 0.77 | LMNA (0.60) | SNCANPC1RAB9ANSD2DUSP3 | |
| SCHEMBL29429154 | 0.77 | LMNA (0.60) | SNCANPC1RAB9ANSD2DUSP3 | |
| SCHEMBL574853 | 0.75 | LMNA (0.58) | SNCANPC1RAB9ANSD2DUSP3 | |
| SCHEMBL1433007 | 0.75 | LMNA (0.58) | SNCANPC1RAB9ANSD2DUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991009020-A2 | PRODUCTION OF 5-(4'-HYDROXYPHENYL)HYDANTOIN AND D-p-HYDROXYPHENYLGLYCINE FROM 4-HYDROXYACETOPHENONE | HOECHST CELANESE CORPORATION (US) | 1991-06-27 | — | — | WO | disclosed |