Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 4/20 | 0.46 |
| ▸ | NSD2 | O96028 | 2/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | NT5E | P21589 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27425328 | 0.86 | CASP6 (0.45) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL9461718 | 0.81 | CASP6 (0.50) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL27481027 | 0.79 | KMT2A (0.51) | KMT2AGAAMEN1USP2KEAP1 | |
| SCHEMBL1705399 | 0.78 | KMT2A (0.64) | KMT2AGAAMEN1USP2KEAP1 | |
| SCHEMBL13730299 | 0.77 | CASP6 (0.49) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL11669819 | 0.76 | HKDC1 (0.48) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL4881379 | 0.75 | CASP6 (0.57) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL987611 | 0.74 | ALDH1A1 (0.65) | KMT2AGAAMEN1USP2KEAP1 | |
| SCHEMBL6205724 | 0.74 | CASP6 (0.55) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL1413155 | 0.73 | HSD17B10 (0.54) | CASP6NSD2DUSP3PTPN5PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037449-A | For dyeing or printing cotton or wool | CIBA-GEIGY CORPORATION (US) | 1991-08-06 | — | — | US | disclosed |
| EP-0304924-A2 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1989-03-01 | — | — | EP | disclosed |