Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.48 |
| ▸ | MAPT | P10636 | 9/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873806 | 0.82 | KMT2A (0.68) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL9875557 | 0.81 | MAPT (0.48) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL9875455 | 0.71 | MEN1 (0.53) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL7048797 | 0.70 | ALDH1A1 (0.44) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL419811 | 0.65 | KMT2A (1.00) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL14194451 | 0.65 | KMT2A (0.81) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL13952316 | 0.64 | POLB (0.60) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL12698975 | 0.64 | KMT2A (0.41) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL6731372 | 0.63 | KMT2A (0.64) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL14197581 | 0.61 | KMT2A (0.69) | ALDH1A1MAPTKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997805-A | Heat sensitive recording material containing chromogenic dicyanomethylenepyrazolinones | CIBA-GEIGY CORPORATION (US) | 1991-03-05 | — | — | US | disclosed |
| US-4950754-A | Chromogenic dicyanomethylenepyrazolinones | CIBA-GEIGY CORPORATION (US) | 1990-08-21 | — | — | US | disclosed |
| US-4916234-A | PYRAZOLONE DYES, THERMOGRAPHY | CIBA-GEIGY CORPORATION (US) | 1990-04-10 | — | — | US | disclosed |