Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | KAT8 | Q9H7Z6 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873806 | 0.89 | KMT2A (0.68) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL6736416 | 0.76 | KMT2A (0.49) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL14862034 | 0.71 | AGER (0.43) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL9874093 | 0.71 | ALDH1A1 (0.48) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL14194451 | 0.69 | KMT2A (0.81) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL486130 | 0.68 | MAPT (0.45) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL486129 | 0.68 | MAPT (0.45) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL14197581 | 0.66 | KMT2A (0.69) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL6731500 | 0.65 | AMY1A (0.55) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL18025778 | 0.64 | MAPT (0.66) | MEN1KMT2AMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997805-A | Heat sensitive recording material containing chromogenic dicyanomethylenepyrazolinones | CIBA-GEIGY CORPORATION (US) | 1991-03-05 | — | — | US | disclosed |
| US-4950754-A | Chromogenic dicyanomethylenepyrazolinones | CIBA-GEIGY CORPORATION (US) | 1990-08-21 | — | — | US | disclosed |
| US-4916234-A | PYRAZOLONE DYES, THERMOGRAPHY | CIBA-GEIGY CORPORATION (US) | 1990-04-10 | — | — | US | disclosed |