Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | GALK1 | P51570 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874093 | 0.81 | ALDH1A1 (0.48) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL9873806 | 0.81 | KMT2A (0.68) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL5711337 | 0.74 | MAPT (0.50) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL27254123 | 0.71 | MAPT (0.48) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL9875455 | 0.70 | MEN1 (0.53) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL27244205 | 0.68 | MAPT (0.45) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL9525436 | 0.68 | MAPT (0.58) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL9525442 | 0.68 | MAPT (0.58) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL28967912 | 0.67 | MEN1 (0.71) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL28967915 | 0.67 | MEN1 (0.71) | MAPTMEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997805-A | Heat sensitive recording material containing chromogenic dicyanomethylenepyrazolinones | CIBA-GEIGY CORPORATION (US) | 1991-03-05 | — | — | US | disclosed |
| US-4950754-A | Chromogenic dicyanomethylenepyrazolinones | CIBA-GEIGY CORPORATION (US) | 1990-08-21 | — | — | US | disclosed |
| US-4916234-A | PYRAZOLONE DYES, THERMOGRAPHY | CIBA-GEIGY CORPORATION (US) | 1990-04-10 | — | — | US | disclosed |