Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.53 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.53 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.52 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.52 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.52 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.52 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.52 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.52 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.52 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.52 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.52 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.52 |
| ▸ | PSMB4 | P28070 | 2/20 | 0.52 |
| ▸ | PSMB6 | P28072 | 2/20 | 0.52 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.52 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.52 |
| ▸ | PSMB3 | P49720 | 2/20 | 0.52 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.52 |
| ▸ | PSMA6 | P60900 | 2/20 | 0.52 |
| ▸ | PSMA8 | Q8TAA3 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874778 | 1.00 | SOAT2 (0.53) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL9873777 | 1.00 | SOAT2 (0.53) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL9873967 | 0.89 | CNR1 (0.59) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL9873961 | 0.89 | CNR1 (0.59) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL8993787 | 0.79 | SOAT2 (0.64) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL28757288 | 0.78 | SOAT1 (0.56) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL1152329 | 0.78 | SOAT1 (0.56) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL17612180 | 0.78 | SOAT1 (0.56) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL9874760 | 0.78 | SOAT2 (0.55) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| Potassium SCHEMBL31403449 | 0.77 | SOAT1 (0.54) | SOAT2SOAT1PSMB11PSMA7PSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0245687-B1 | SUBSTITUTED PYRIMIDINE AMIDES OF OLEIC OR LINOLEIC ACID AS INHIBITORS OF ACYL-COA CHOLESTEROL ACYLTRANSFERASE | WARNER-LAMBERT COMPANY (US) | 1991-02-27 | — | — | EP | claimed |
| US-4722927-A | ANTICHOLESTEROL AGENTS | WARNER-LAMBERT COMPANY (US) | 1988-02-02 | — | — | US | claimed |
| EP-0245687-A1 | Substituted pyrimidine amides of oleic or linoleic acid as inhibitors of acyl-coa cholesterol acyltransferase | WARNER-LAMBERT COMPANY (US) | 1987-11-19 | — | — | EP | claimed |
| US-4722927-A | ANTICHOLESTEROL AGENTS | WARNER-LAMBERT COMPANY (US) | 1988-02-02 | — | — | US | disclosed |
| EP-0245687-A1 | Substituted pyrimidine amides of oleic or linoleic acid as inhibitors of acyl-coa cholesterol acyltransferase | WARNER-LAMBERT COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |