Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874190 | 0.75 | PRMT5 (0.37) | PRMT5WDR77HPGDRECQLKDM4E | |
| SCHEMBL9690259 | 0.74 | KCNH2 (0.41) | PRMT5WDR77HPGDRECQLKDM4E | |
| SCHEMBL9689617 | 0.63 | DRD2 (0.55) | PRMT5WDR77KDM4EKMT2AKCNH2 | |
| SCHEMBL4395710 | 0.61 | LMNA (0.48) | HPGDRECQLKDM4ELMNAMEN1 | |
| SCHEMBL1474479 | 0.60 | HPGD (0.63) | HPGDRECQLKDM4ELMNAMEN1 | |
| SCHEMBL8374389 | 0.60 | HPGD (0.61) | HPGDRECQLLMNASMN1; SMN2 | |
| SCHEMBL11696035 | 0.59 | GRIN1 (0.55) | HPGDRECQLKDM4EMEN1KMT2A | |
| SCHEMBL3847673 | 0.59 | HPGD (0.57) | HPGDRECQLKDM4ELMNAMEN1 | |
| SCHEMBL3875386 | 0.59 | ALDH1A1 (0.59) | HPGDRECQLKDM4ELMNAMEN1 | |
| Hydrochloric Acid SCHEMBL11695954 | 0.58 | GRIN1 (0.54) | HPGDRECQLMEN1KMT2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990509-A | Sulfonamide anti-arrhythmic agents | PFIZER INC. (US) | 1991-02-05 | — | — | US | disclosed |