Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875486 | 0.88 | KMT2A (0.60) | KMT2AMEN1ALDH1A1KDM4ENPC1 | |
| SCHEMBL1905334 | 0.86 | KMT2A (0.49) | KMT2AMEN1ALDH1A1KDM4ENPC1 | |
| SCHEMBL8327448 | 0.84 | NPC1 (0.44) | KMT2AMEN1ALDH1A1KDM4ENPC1 | |
| SCHEMBL23145042 | 0.83 | KMT2A (0.44) | KMT2AMEN1ALDH1A1KDM4ENPC1 | |
| SCHEMBL29843352 | 0.83 | KMT2A (0.44) | KMT2AMEN1ALDH1A1KDM4ENPC1 | |
| SCHEMBL1906531 | 0.83 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1KDM4ENPC1 | |
| SCHEMBL8568056 | 0.81 | KDM4E (0.49) | KMT2AMEN1ALDH1A1KDM4ENPC1 | |
| SCHEMBL11331742 | 0.80 | MAPK8 (0.43) | KMT2AMEN1ALDH1A1KDM4ENPC1 | |
| SCHEMBL12089379 | 0.80 | KMT2A (0.48) | KMT2AMEN1ALDH1A1KDM4ENPC1 | |
| SCHEMBL6286366 | 0.79 | DYRK1A (0.50) | KMT2AMEN1ALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026711-A | Prevention and treatment of cardiovascular disorders and infections states; anxiolytic and anti-allergic agents | SANOFI (FR) | 1991-06-25 | — | — | US | disclosed |